ZeuS or ZBot is just one tool of an international cybercrime ring with one goal to steal your money. Clicking a link in an innocent-looking e-mail could open your system to attack. For full protection against all possible infection vectors, you absolutely need to install a security suite on any computer that has Internet access. The statistical detection used in Norton Internet Security 2011 is especially effective against brand-new variants of ZeuS. If you remotely access accounts with massive balances you may want to add yet another protective layer.
Source: https://thehackernews.com/2010/12/beware-of-zeus-trojan-attack.html