Microsoft acknowledged a new known issue impacting several Windows versions and leading to unexpectedly slow startups on computers configured to use persistent memory. The bug impacts both client and server Windows versions according to Microsoft. The company is also working on a resolution for this new issue that will be addressed in future Windows releases, as part of updates that will also come with supplementary optimization in the startup path. The issue is only affected if the persistent memory is used in memory mode since using it as a storage device will not influence system startup times.
Source: https://www.bleepingcomputer.com/news/microsoft/microsoft-warns-of-windows-slow-startup-due-to-persistent-memory/