The Folding@Home project is a distributed computing project that allows people to donate their CPU cycles to research diseases and news drugs and treatments. Microsoft has released a PowerShell script that lets you quickly and securely get up and running with the program in the Windows 10 Sandbox. This feature is only available on Windows 10 Pro or Enterprise Insider builds 18362 or later. The best part is that you can simply close the Windows Sandbox when done and no installed files will be left installed behind. When you are ready to contribute again, you can launch the script to start donating your CPU again.
Source: https://www.bleepingcomputer.com/news/microsoft/microsoft-script-installs-folding-home-in-windows-10s-sandbox/