The main site for the PHP-Nuke content management system software has been compromised and is serving malicious iFrame exploits to visitors. The attack uses the common iFrame-redirection technique to hijack users browsers and send them off to a malicious site. The code on that site is highly obfuscated and contains exploits for three separate vulnerabilities, two in Internet Explorer and one in Adobe Reader. The first attack tries to exploit a four-year-old flaw in IE; the second attack uses a Java exploit.
Source: https://threatpost.com/main-php-nuke-site-compromised-050710/73938/