Microsoft sacrificed easy access to Windows Safe Mode to increase the boot speed of Windows 10. Safe Mode with Networking is a special mode that you can boot Windows into that loads a minimal set of drivers, Windows services, and does not load any applications that are set to autostart. This mode is especially useful when trying to remove files that may be in use, applications that won’t uninstall properly, uninstalling or installing drivers, and removing malware. The easiest way to begin the process of booting into this mode is from the Windows 10 login screen.
Source: https://www.bleepingcomputer.com/tutorials/how-to-start-windows-10-in-safe-mode-with-networking/