2010 was known for the emergence of Stuxnet, the first piece of malware specifically designed to sabotage nuclear power plants. Social networking users befriended Trojan.Koobface, a piece of. malware that used to spread via social platforms such as Facebook, Twitter and Hi5. The early 90s marked an important milestone for the traditional antivirus industry that was relying on string signatures to statically identify malware. The emergence of Chameleon, an e-threat actually able to mutate its code after each infection in order to trick AV scanners and evade detection, signaled that it was time for the industry to switch to more advanced defense technologies.”]
Source: https://www.bitdefender.com/blog/hotforsecurity/duqu-another-worlds-most-advanced-piece-of-malware/