Microsoft has released its largest-ever bundle of patches, pushing out 16 updates that fix a total of 49 individual vulnerabilities. The patches include updates for six critical vulnerabilities, most notably a huge fix for some remote code-execution bugs in various versions of Internet Explorer. A pair of uninitialized memory corruption vulnerabilities in IE 6 up through IE 8 are deemed the mst dangerous by Microsoft. One of the other bugs that Microsoft patched is MS010-073, one of the vulnerabilities used in the Stuxnet attack.
Source: https://threatpost.com/microsoft-releases-huge-patch-tuesday-update-49-bugs-101210/74568/