Microsoft is introducing a new feature called Windows Sandbox that will allow you to safely run executables in a throw-away virtualized sandbox without fear of your regular Windows install becoming infected. This feature will be available starting in the upcoming Windows 10 Pro and Enterprise Insider build 18305. Anything running in this sandboxed desktop environment is isolated from yuor normal Windows 10 operating system and cannot affect it. It is not known if installed applications on the host OS will also be included in the sandbox.
Source: https://www.bleepingcomputer.com/news/microsoft/microsofts-windows-sandbox-runs-programs-in-an-isolated-desktop/