Informatics is by its nature multidisciplinary, and these varied stakeholders are governed by value systems that differ in significant ways. The resulting IT systems and use cases present ethical challenges including threats to patient autonomy and shared decision-making, the provider-patient relationship, and the Big Data that is leveraged to inform evidence-based medicine. Despite their many benefits, both actual and aspirational, health information technology offers no panacea for the ills of our beleaguered healthcare system.”]